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MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

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The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact of MDM2 del1518 on risk of ovarian and endometrial cancer. |

TÀI LIỆU LIÊN QUAN

A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk