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Engrailed-2 (EN2) – a novel biomarker in epithelial ovarian cancer

Epithelial ovarian cancer is a common malignancy, with no clinically approved diagnostic biomarker. Engrailed-2 (EN2) is a homeodomain-containing transcription factor, essential during embryological neural development, which is dysregulated in several cancer types. | Engrailed-2 EN2 a novel biomarker in epithelial ovarian cancer