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Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells
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Despite its relatively low incidence, pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths because of the aggressive growth/metastasis of the tumor, the lack of early symptoms, and the poor treatment options. Basic research to identify potential therapeutic targets for PDAC is greatly needed. | Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells