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Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia
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The tumor suppressor protein phosphatase and tensin homolog (PTEN) is a key regulator of the PI3K/ AKT pathway which is frequently altered in a variety of tumors including a subset of acute B-lymphoblastic leukemias (B-ALL). | Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia