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Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis: A comparison study

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Analysis of high microsatellite instability (MSI-H) phenotype in colorectal carcinoma (CRC) is important for evaluating prognosis and choosing a proper adjuvant therapy. Although the conventional MSI analysis methods such as polymerase chain reaction (PCR) fragment analysis and immunohistochemistry (IHC) show high specificity and sensitivity, there are substantial barriers to their use. | Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis A comparison study

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