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Benzimidazole resistance: An overview

Anthelmintic drug resistant rising the major threat for the animal population. Benzimidazole group of anthelmintic drug are most popular and used drug in nematodal control strategy. High treatment frequency, single-drug regimens, targeting the mass treatments, under-dosing, improper use of anthelmintic, improper management, unguided and unaddressed policy of nematodal control leads to the resistant among the animal population which become main source of transferring and migrating the resistant to another. Selection pressure act majorly in escaping the treatment. Genetic as well as acquired factors are also play a role diversely in the resistance. Based on the current available knowledge and parameters, we have reviewed the epidemiological consideration of persistent prevalence, factors, and mechanism of benzimidazole (BZ) resistance which may further open the door for the researcher, investigator and policy maker for its control and standardizing the guideline. | Benzimidazole resistance An overview