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MTH1 deficiency selectively increases noncytotoxic oxidative DNA damage in lung cancer cells: More bad news than good
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Targeted therapies are based on exploiting cancer-cell-specific genetic features or phenotypic traits to selectively kill cancer cells while leaving normal cells unaffected. Oxidative stress is a cancer hallmark phenotype. | MTH1 deficiency selectively increases noncytotoxic oxidative DNA damage in lung cancer cells More bad news than good