Đang chuẩn bị liên kết để tải về tài liệu:
The clonal evolution of two distinct T315Ipositive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: A case report

Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ

The treatment of Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL) patients who harbor the T315I BCR-ABL1 mutation or who have two or more mutations in the same BCR-ABL1 molecule is particularly challenging since first and second-generation Tyrosine Kinase Inhibitors (TKIs) are ineffective. | The clonal evolution of two distinct T315Ipositive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy A case report