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Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery
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Neuroblastoma is a paediatric cancer that despite multimodal therapy still has a poor outcome for many patients with high risk tumours. Retinoic acid (RA) promotes differentiation of some neuroblastoma tumours and cell lines, and is successfully used clinically, supporting the view that differentiation therapy is a promising strategy for treatment of neuroblastoma. | Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery