Đang chuẩn bị liên kết để tải về tài liệu:
Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients

Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Parkin in breast cancer remains largely unknown. | Parkin gene mutations are not common but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients