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Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab

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KRAS mutations have been characterized as the major predictive biomarkers for resistance to cetuximab treatment. However, studies indicate that not all KRAS mutations are associated with equivalent treatment outcomes. | Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab