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A bioanalytical UHPLC based method used for the quantifcation of Thymoquinone-loaded-PLGA-nanoparticles in the treatment of epilepsy

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To formulate a nanoformulation (PLGA-NPs) and to improve brain bioavailability for thymoquinone (THQ) through intranasal (i.n.) drug delivery, using a newly UHPLC-PDA developed the method and validated. Five different THQ-PLGA-NPs (THQ-N1 to THQ-N5) were prepared by emulsion solvent evaporation method. | A bioanalytical UHPLC based method used for the quantifcation of Thymoquinone-loaded-PLGA-nanoparticles in the treatment of epilepsy

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A bioanalytical UHPLC based method used for the quantifcation of Thymoquinone-loaded-PLGA-nanoparticles in the treatment of epilepsy