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Maintenance of human chondrogenic phenotype on a dendrimer-immobilized surface for an application of cell sheet engineering

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Dedifferentiation of chondrocytes during cell expansion is one of the barriers in tissue construction for cartilage repair. The one-step process of cell expansion and maintenance of chondrogenic activity could be obtained using the G5 surface. Human chondrocyte sheets were successfully constructed with high chondrogenic activity. | Maintenance of human chondrogenic phenotype on a dendrimer-immobilized surface for an application of cell sheet engineering