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Inducing goat pluripotent stem cells with four transcription factor mRNAs that activate endogenous promoters

Core promoter regions and functional transcription binding sites of the four reprogramming genes were identified. Epigenetic regulation was revealed to participate in mRNA induced iPSCs formation. Our study provides a safe and efficient approach for goat. iPSCs generation. | Inducing goat pluripotent stem cells with four transcription factor mRNAs that activate endogenous promoters