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Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo
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Rational design of AAV capsids is a simple method for enhancing AAV transduction efficiency. AAV-DJ is a highly recombinogenic hybrid vector created from DNA shuffling of eight AAV serotypes, which mediates efficient gene expression both in vitro and in vivo. | Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo