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Continuous enhancement of iturin A production by Bacillus subtilis with a stepwise two-stage glucose feeding strategy

The lipopeptide antibiotic iturin A is an attractive biopesticide with the potential to replace chemicalbased pesticides for controlling plant pathogens. However, its industrial fermentation has not been realized due to the high production costs and low product concentrations. | Continuous enhancement of iturin A production by Bacillus subtilis with a stepwise two-stage glucose feeding strategy