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Prevalence of ESBL in isolates of Klebsiella Pneumoniae and E. coli in suspected cases of neonatal septicemia in tertiary care Hospital in North Maharashtra, India

Neonatal sepsis is a significant cause of morbidity and mortality in newborns and is responsible for 30 – 50 % of total neonatal deaths. Multidrug resistant Gram negative bacilli belonging to the family Enterobcteriaceae have been increasingly responsible for infections among the neonates admitted to the NICU in many countries including India. The study was conducted to know prevalence of ESBL production in Klebsiella pneumoniae and Escherichia coli in NICU so that we can help clinicians to avoid injudicious use of antibiotics. The present study was carried out from July 2017 to December 2018 in Microbiology Department of the rural medical college in North Maharashtra. A total of 200 samples of blood cultures from neonates admitted in the NICU were processed for the study. 2 ml blood from the neonates was collected under aseptic precautions and the samples were inoculated on blood culture bottle containing Brain Heart Infusion (BHI) broth. | Prevalence of ESBL in isolates of Klebsiella Pneumoniae and E. coli in suspected cases of neonatal septicemia in tertiary care Hospital in North Maharashtra, India