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Raltegravir does not revert efflux activity of MDR1-P-glycoprotein in human MDR cells

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Raltegravir (Isentress®)(RALT) has demonstrated excellent efficacy in both treatment-experienced and naïve patients with HIV-1 infection, and is the first strand transfer integrase inhibitor to be approved for use in HIV infected adults worldwide. | Raltegravir does not revert efflux activity of MDR1-P-glycoprotein in human MDR cells