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Does antihypertensive treatment with renin-angiotensin system inhibitors prevent the development of diabetic kidney disease?

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide. Reninangiotensin system (RAS) inhibitors are the first-line treatment for diabetic patients with hypertension. However, whether RAS inhibitors prevent the development of DKD remains controversial. | Does antihypertensive treatment with renin-angiotensin system inhibitors prevent the development of diabetic kidney disease?