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Lecture Chemical process control - Chapter 23

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a | Chapter 23 Biosystems Control Design Chapter 23 addresses a variety of synthesis problems in the field of biosystems Pharmaceutical Operations Bioreactors Crystallizers Granulation Drug Delivery Type 1 Diabetes Blood Pressure Control Cancer Treatment Controlled Treatment for HIV AIDS Cardiac Assist Devices 1 Chapter 23 Base Medium Inoculant Offline Measurements - Total cell count - Viable cell count - Osmotic pressure -dco2 - Glucose - Glutamine Off Gas gas chromatograph Aừ co2 Aừ co2 02 N2 - Lactate - Ammonia - Other amino acids - Titer 11 Harvest Figure 23.1 Schematic of a typical industrial fermentor. 2 Chapter 23 Figure 23.2 Step response of fermentor model to symmetric changes in dilution of magnitude 10 from the nominal value of D 0.202 h-1.