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Human trabecular meshwork progenitors

This article reviews human trabecular meshwork progenitor therapy and discusses its potential applications for curing human eye blindness. | 704 Int. J. Med. Sci. 2019 Vol. 16 ivyspring international publisher Review InternationalJournal ofMedicalSciences 2019 16 5 704-710. doi 10.7150 ijms.32089 Human Trabecular Meshwork Progenitors Qin Zhu1 Yuan Zhang2 Sean Tighe2 Yongsong Liu3 Yingting Zhu2 and Min Hu1 1. Department of Ophthalmology Fourth Affiliated Hospital of Kunming Medical University the Second People s Hospital of Yunnan Province Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology 2017DG008 Provincial Innovation Team for Cataract and Ocular Fundus Disease The Second People s Hospital of Yunnan Province 2017HC010 Expert Workstation of Yao Ke 2017IC064 Kunming 650021 China 2. Tissue Tech Inc. Ocular Surface Center and Ocular Surface Research Education Foundation Miami FL 33173 USA 3. Department of Ophthalmology Yan An Hospital of Kunming City Kunming 650051 China E Corresponding authors Min Hu M.D. Ph.D. Department of Ophthalmology Fourth Affiliated Hospital of Kunming Medical University Second People s Hospital of Yunnan Province Kunming 650021 China Telephone 0118615087162600 Fax 011860871-65156650 E-mail fudanhumin@sina.com or Yingting Zhu Ph.D. TissueTech Inc. 7000 SW 97th Avenue Suite 212 Miami FL 33173. Telephone 786 456-7632 Fax 305 274-1297 E-mail yzhu@tissuetechinc.com Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution CC BY-NC license https creativecommons.org licenses by-nc 4.0 . See http ivyspring.com terms for full terms and conditions. Received 2018.12.07 Accepted 2019.03.04 Published 2019.05.10 Abstract Trabecular meshwork TM cells are a group of progenitors that have the ability to become adipocytes chondrocytes and endothelial cells. Therefore those adult corneal progenitors may be used as an effective therapy for trabecular meshwork diseases such as glaucoma corneal endothelial dysfunctions such as blindness due to corneal endothelial dysfunction .