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Matrigel scaffolding enhances BMP9-induced bone formation in dental follicle stem/precursor cells

Bone tissue engineering requires a combination of cells, efficient biochemical and physicochemical factors, and biocompatible scaffolds. In this study, we evaluated the potential use of injectable Matrigel as a scaffold for the delivery of rat dental follicle stem/precursor cells (rDFSCs) transduced by bone morphogenetic protein (BMP) 9 to enhance osteogenic differentiation in vitro and promote ectopic bone formation in vivo. | Matrigel scaffolding enhances BMP9-induced bone formation in dental follicle stem/precursor cells