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SiRNA-mediated RRM2 gene silencing combined with cisplatin in the treatment of epithelial ovarian cancer in vivo: An experimental study of nude mice

We aimed to explore small interfering (si)RNA silencing of ribonucleotide reductase M2 (RRM2) gene combined with cisplatin for the treatment of human ovarian cancer in nude mice models of subcutaneous transplantation of tumor cells. | SiRNA-mediated RRM2 gene silencing combined with cisplatin in the treatment of epithelial ovarian cancer in vivo: An experimental study of nude mice