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Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in breast cancer: A Sardinian preliminary case-control study
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Two common polymorphisms in the MTHFR gene, C677T and A1298C, are associated with reduced enzyme activity and may be associated with breast cancer susceptibility. We performed a case-control study to investigate the association between the two SNPs in the MTHFR gene and risk of breast cancer. In total, 58 breast cancer patients and 58 unaffected controls were enrolled in the study. | Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in breast cancer: A Sardinian preliminary case-control study