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An undergraduate experiment using cyclodextrin – assisted sensitive fluorescence detection and quantitation of dapsone drug in wastewater samples

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The guest-host interaction between Dapsone drug and β-cyclodextrin (β-CD) was investigated using fluorescence spectroscopy, 1 H-NMR, and liquid chromatography with fluorescence detection. The optimized conditions for the interaction were investigated by spectrofluorometry and were found to be at 0.2 mg/mL (0.176 mM) of β-CD and pH 8.8. For these conditions, very low concentration of Dapsone drug of 2.4 ng/mL (12.97 nM) can be detected. | An undergraduate experiment using cyclodextrin – assisted sensitive fluorescence detection and quantitation of dapsone drug in wastewater samples

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