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The antioxidant activity of some medicinal plants
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The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. | Turk J Biol 32 (2008) 197-202 © TÜBİTAK The Antioxidant Activity of Some Medicinal Plants Prateek Kumar JAIN, Veerasamy RAVICHANDRAN, Simant SHARMA, Ram K. AGRAWAL Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar (M.P.), 470 003 - INDIA Received: 15.08.2007 Abstract: The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC50 value of 7.92 ± 0.1 μg/ml, followed by Asparagus racemosus, with an IC50 value of 9.28 ± 0.2 μg/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC50 value of 44.48 ± 1.8 μg/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus > Terminalia chebula > Emblica officinalis > Centella asiatica > Withania somnifera > Terminalia bellerica > Glycyrrhiza glabra > Evolvulus alsinoides > Zingiber officinale > Andrographis paniculata. According to the lipid peroxidation assay the extracts of Emblica officinalis and Evolvulus alsinoides showed the greatest effectiveness, with inhibition values of 39.14 ± 2.1% and 36.38 ± 1.3%, respectively, at the 100-μg/m concentration (P Terminalia chebula > Emblica officinalis > Centella asiatica > Withania somnifera > Terminalia bellerica > Glycyrrhiza glabra > Evolvulus alsinoides > Zingiber officinale > Andrographis paniculata şeklinde sıralanmıştır. Lipit peraksidasyon denemesinde Emblica officinalis ve Evolvulus alsinoides en yüksek etkiyi göstermiştir. İnhibisyon değerleri 100 μg/ml konsantrasyonda 39,14 ± 2,1% ve 36,38 ± 1,3% şeklinde hesaplanmıştır (P Asparagus racemosus > Withania somnifera> Evolvulus alsinoides > Terminalia chebula > Centella asiatica > Terminalia bellerica > Andrographis paniculata > Glycyrrhiza glabra > .