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Evaluation of the outcomes of treating pituitary tumor by rotating gamma knife at the Nuclear Medicine and Oncology Center, Bachmai hospital

Objectives: To evaluate treatment outcomes of rotating Gamma knife radiosurgery (RGKR) for pituitary adenomas at the Nuclear Medicine and Oncology Center, Bachmai Hospital. Subjects and methods: A prospective interventional study was conducted on 48 patients, whowere treated with rotating Gamma knife for pituitary tumor. All patients had size of tumor < 5 cmon MRI and recruited in between April, 2008 and April, 2016. | Journal of military pharma-medicine no6-2017 EVALUATION OF THE OUTCOMES OF TREATING PITUITARY TUMOR BY ROTATING GAMMA KNIFE AT THE NUCLEAR MEDICINE AND ONCOLOGY CENTER, BACHMAI HOSPITAL Nguyen Thi Minh Phuong*; Mai Trong Khoa** Doan Van De***; Tran Quoc Hung* Summary Objectives: To evaluate treatment outcomes of rotating Gamma knife radiosurgery (RGKR) for pituitary adenomas at the Nuclear Medicine and Oncology Center, Bachmai Hospital. Subjects and methods: A prospective interventional study was conducted on 48 patients, who were treated with rotating Gamma knife for pituitary tumor. All patients had size of tumor 60 years old: 7 patients (14,6%). The study on 48 patients with pituitary tumors using rotating Gamma radiography at the Center for Nuclear Medicine and Oncology, Bachmai Hospital showed that: The majority of patients in the age group of 31 - 45 years old, the lowest age was 21, the highest age was 78, the average was 44.58 ± 12.84 years old. The percentage of male accounted for 33.3%; females accounted for 66.7%. 2. Distribution of patients by gender. Figure 1: Patient distribution. In the study group, the proportion of male patients was 33.3% male, female was 66.7%. Heng Wan's study (2007) [3] reported that the average age of patients with pituitary tumors was 44.58 ± 12.84 years old and the proportion of women was higher than men. 3. Medical history before surgery. No interventions: 6 patients medication interventions: 30 (12.5%); patients (62.5%); surgical interventions: 12 patients (25.0%). Most patients have received medication or surgical treatment for recurrence. 12.5% of the patients who received no treatment were indicated to use radiotherapy. According to Faglia G, 92% of patients with pituitary gland tumors who had been treated with Gamma irradiation had failed to response to prior medication treatments. 171 Journal of military pharma-medicine no6-2017 4. Irradiation dosages. Table 1: Dose (Gy) Mean dose (X) Standard .