tailieunhanh - Lecture Principles of biochemistry - Chapter 16 (part 3): Fatty acid synthesis

In this chapter 16 (part 3), you will: Know the reactions/enzymes/co-substrates/intermediates of fatty acid synthesis, be able to recognize the intermediates of one round of fatty acid synthesis, know the co-enzymes and co-substrates involved in each step, know how the fatty acid synthetic machinery is organized in plants, bacteria and animals. | Chapter 16 (Part 3) Fatty acid Synthesis ACP vs. Coenzyme A Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP Acetyl-CoA Carboxylase Regulation of Acetyl-CoA Carboxylase (ACCase) Animal Fatty Acid Synthase Further Processing of Fatty acids: Desaturation and Elongation Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine acyltransferase | Chapter 16 (Part 3) Fatty acid Synthesis ACP vs. Coenzyme A Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP Acetyl-CoA Carboxylase Regulation of Acetyl-CoA Carboxylase (ACCase) Animal Fatty Acid Synthase Further Processing of Fatty acids: Desaturation and Elongation Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine . | Chapter 16 (Part 3) Fatty acid Synthesis ACP vs. Coenzyme A Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP Acetyl-CoA Carboxylase Regulation of Acetyl-CoA Carboxylase (ACCase) Animal Fatty Acid Synthase Further Processing of Fatty acids: Desaturation and Elongation Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine acyltransferase | Chapter 16 (Part 3) Fatty acid Synthesis ACP vs. Coenzyme A Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP Acetyl-CoA Carboxylase Regulation of Acetyl-CoA Carboxylase (ACCase) Animal Fatty Acid Synthase Further Processing of Fatty acids: Desaturation and Elongation Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine . | Chapter 16 (Part 3) Fatty acid Synthesis ACP vs. Coenzyme A Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP Acetyl-CoA Carboxylase Regulation of Acetyl-CoA Carboxylase (ACCase) Animal Fatty Acid Synthase Further Processing of Fatty acids: Desaturation and Elongation Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine acyltransferase