tailieunhanh - Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Document "Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis" presentation of content: Epidemiology, pathogenesis and risk factors, diagnosis, management, summary, references. | World Gastroenterology Organisation Global Guidelines Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis June 2012 Review Team Douglas Zaigham Frank Peter Aamir Khean-Lee Saeed S. Vasily Maribel Manuel Juan Francisco Shiv Davor Alan . Muhammed Justus Anton LaBrecque chair Abbas Anania Ferenci Ghafoor Khan Goh Hamid Isakov Lizarzabal Mojica Pernaranda Rivera Ramos Sarin Stimac Thomson Umar Krabshuis LeMair USA Pakistan USA Austria Pakistan Malaysia Pakistan Russia Venezuela Colombia Mexico India Croatia Canada Pakistan France Netherlands World Gastroenterology Organisation 2012 WGO Global Guidelines NAFLD NASH long version 2 Contents 1 Introduction 3 2 Epidemiology 5 3 Pathogenesis and risk factors 8 4 Diagnosis 11 5 Management 18 6 Summary 22 References 23 List of tables Table 1 Mortality in NAFLD NASH 3 Table 2 Clinical identification of the metabolic syndrome 4 Table 3 Regional obesity overweight data representative examples 5 Table 4 Overweight and obesity summary of prevalence by region 2004 6 Table 5 Estimated prevalences of NAFLD and NASH 7 Table 6 Risk factors and associated conditions 9 Table 7 Calculation of insulin resistance 9 Table 8 NASH scoring system in morbid obesity 9 Table 9 NASH survival rates in comparison with simple steatosis and alcoholic steatohepatitis 10 Table 10 Disease progression from NAFLD to NASH to cirrhosis liver failure and HCC 10 Table 11 NASH Clinical Research Network histological scoring system 13 Table 12 Diagnostic tests for fatty liver 14 Table 13 Diagnostic cascade for extensive medium and limited resources 17 Table 14 Patient follow-up tests and their frequency 20 Table 15 Therapy cascades for extensive medium and limited resources 20 List of figures Fig. 1 Estimated prevalence of obesity BMI 25 in males and females aged 15 2010 6 Fig. 2 The multi-hit hypothesis for nonalcoholic steatohepatitis NASH 8 Fig. 3 Management algorithm for NAFLD 14 Fig. 4 Algorithm for liver biopsy in patients with suspected .