tailieunhanh - Phenolic Constituents of Lonicera japonica Thunb.,Caprifoliaceae, of Vietnam

Caffeic acid, chlorogenic acid, methyl ester of chlorogenic acid, tricin, apigenin, 4’-O- methyl ether of apigenin (acacetin), quercetin and 3’-O-methyl ether of quercetin were isolated from the flowers of Lonicera japonica Thunb., Caprifoliaceae, grown as a medicinal plant for commercial purposes in Vietnam. Their chemical structures were determined by EIMS, 1 H NMR, 13 C NMR, DEPT, COSY, HMQC and HMBC. | Journal of Chemistry Vol. 43 4 P. 489 - 493 2005 PHENOLIC CONSTITUENTS OF LONICERA JAPONICA Thunb. CAPRIFOLIACEAE OF VIETNAM Received 8th-December 2003 PHAN MINH GIANG NGUyEN THI MINH HANG PHAN TONG SON College of Natural Science Vietnam National University Hanoi SUMMARy Caffeic acid chlorogenic acid methyl ester of chlorogenic acid tricin apigenin 4 -O-methyl ether of apigenin acacetin quercetin and 3 -O-methyl ether of quercetin were isolated from the flowers of Lonicera japonica Thunb. Caprifoliaceae grown as a medicinal plant for commercial purposes in Vietnam. Their chemical structures were determined by EIMS H NMR J3C nMr dept cosy HMQC and HMBC. I - INTRODUCTION The medicinal properties and popular use of Lonicera japonica Thunb. Caprifoliaceae Vietnamese name kim ng n are well documented 1 2 . As the first group taking the attempt to investigate the chemical constituents of the Vietnamese L. japonica species which is grown as a medicinal plant for commercial purposes recently we isolated -sitosterol 10-nonacosanol chrysin-7-O- -glucoside 3 and 3 Miydroxyurs-12-en-30-oic acid 4 . Further study on the flavonoid-containing ethyl acetate-soluble fraction obtained by successive liquidliquid fractionation of the aqueous MeOH extract of the flowers of L. japonica resulted in the isolation and structure determination of eight phenolic constituents and is reported in this paper. II - EXPERIMENTAL General Experimental Procedures Melting points were measured on an Electrothermal model 9100 and are uncorrected. NMR spectra were obtained on a Bruker Avance 500 NMR spectrometer 500 MHz for 1H-NMR and 125 MHz for 13C-NMR . IR spectra KBr pellet were recorded on a Nicolet Impact 410 FT-IR spectrometer. EIMS 70 eV spectra were measured on a HP 5898B mass spectrometer. Column chromatography CC and FC was carried out on silica gel Merck 15-40 pm and 40 - 63 pm and polyamide 6S Riedel de Haen . Lipophilic Sephadex LH-20 Sigma-Aldrich was used for size-exclusion chromatography.

• Hoá học
• Công nghệ hóa
• Phenolic Constituents
• Lonicera japonica Thunb
• Hóa hữu cơ
• Caffeic acid
• Chlorogenic acid
• Kỹ thuật hệ thống công nghệ hóa học
• Hệ thống công nghệ hóa học
• Công nghệ hóa học
• Tối ưu hóa
• Quá trình công nghệ hóa học
• Phương pháp giải thích
• Quy hoạch toán học
• Phương pháp gradient
• Mô hình hóa công nghệ hóa học
• Nghiên cứu công nghệ hóa học
• Mô tả công nghệ hóa học
• giáo trình công nghệ hóa học
• thiết bị công nghệ hóa học
• bài giảng công nghệ hóa học
• công nghệ hóa chất
• tài liệu công nghệ hóa chất
• áp dụng công nghệ hóa chất
• tìm hiểu công nghệ hóa chất
• nghiên cứu công nghệ hóa chất
• công nghệ hóa dầu
• bài giảng công nghệ hóa dầu
• giáo trình công nghệ hóa dầu
• tài liệu công nghệ hóa dầu
• lý thuyết công nghệ hóa dầu