tailieunhanh - Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species

The as1-casein (as1-Cas) locus in the goat is characterized by a polymorphism, the main feature of which is to be qualitative as well as quantitative. A systematic analysis performed in an autochthon southern Italy breed identified a new rare allele (M), which was characterized at both the protein and genomic level. The M protein displays the slowest electrophoretic mobility of the as1-Cas variants described so far. | Eur. J. Biochem. 269 1293-1303 2002 FEBS 2002 Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species Claudia Bevilacaua1 2 Pasauale Ferranti3 4 Giusennina Garro3 4. Cristina Veltri1 Raffaella Laaoniaro1 BB B w BB bB BB BB w bB WbB w bB bB w BB B BB B BB B B bB B B B BM B w BB BB BB B B B bB BM bB B B bB BB B B B B B bB V BB B B B B B bB B B bB BB B B bB B bB bB BB B B B bB B BB Christine Leroux2 Emilio Pietrola1 Francesco Addeo3 4 Fabio Pilla1 Lina Chianese3 and Patrice Martin2 1 Dipartimento di Scienze Animali Vegetal e dell Ambiente Facoltd di Agraria dell Universita del Molise Campobasso Italy 2Laboratoire de Genetique biochimique et de Cytogenetique INRA Domaine de Vilvert Jouy-en-Josas France 3Dipartimento di Scienza degli Alimenti Facolta di Agraria le Universita di Napoli Federico II Portici Italy 4Istituto di Scienze dell Alimentazione del CNR Avellino Italy The as1-casein as1-Cas locus in the goat is characterized by a polymorphism the main feature of which is to be qualitative as well as quantitative. A systematic analysis performed in an autochthon southern Italy breed identihed a new rare allele M which was characterized at both the protein and genomic level. The M protein displays the slowest electrophoretic mobility of the as1-Cas variants described so far. MS and automated Edman degradation experiments showed that this behavior was due to the loss of two phosphate residues in the multiple phosphorylation site 64SP-SP-SP-SP-SP-E-70E consecutively to a Ser Leu substitution at position 66 of the peptide chain 64S-SP-L-SP-SP-E-70E . This was conhrmed by sequencing a genomic DNA fragment encompassing exon 9 where the 8th codon TCG was shown to be mutated to TTG. Sequencing of amplihed genomic DNA segments spanning the 5 and 3 flanking regions of each exon allowed us to identify 23 single nuc leotide polymorphisms and two insertion deletion events in the coding as well as the noncoding .

• Báo cáo khoa học
• Traditional medicine
• Report medicine
• scientific reports
• medical research
• hemoglobin
• medical knowledge
• Commercial use
• Tadehagi triquetrum (L ) H Ohashi
• Indigenous medicine in Myanmar
• Medicinal plants
• Calotropis gigantea R
• Br
• Traditional medicinal plants
• Local development in Myanmar
• Important role in health care system
• BMC Chemistry
• Trace analysis
• Dispersive solvent
• Traditional Chinese medicine
• Chinese medicine oral liquid
• Veterinary Medicine
• Herbal Medicine
• Varughese George
• Andrographis paniculata
• Chemical Constituents
• alternative medicine
• diagnostic techniques
• Diagnostic therapies
• Chinese medicine
• Medical herbalism
• Massage therapy review
• Lecture Massage therapy review
• Bodywork assessment
• Massage therapy
• Traditional chinese medicine modality
• Acanthospermum hispidum
• Burkina faso
• Pharmacognosic characterization
• Acanthospermum hispidum (Asteraceae)
• Medicinal plant widely
• Active components
• Plasma protein binding
• Research methods
• Doctoral thesis abstract
• Improving accounting work organization
• Accounting work organization
• Traditional medicine hospitals
• Hanoi city
• Vietnamese traditional medicine
• Medicinal herbs
• Ethnic groups
• Community healthcare
• Mountainous area
• Cultural Perspective
• Modern Medicine
• Funding Perspective
• Traditional Oriental
• medicine
• cell proliferation
• oxidation
• breast cancer
• chemical reaction
• gastric cancer
• hormone medicine
• tumor cells
• biochemical studies
• environmental medicine
• Crystal structure