tailieunhanh - Ebook Medical physiology principles for clinical medicine (4th edition): Part 2

(BQ) Part 2 book "Medical physiology principles for clinical medicine" presents the following contents: Respiratory physiology, renal physiology and body fluids, gastrointestinal physiology, temperature regulation and exercise physiology, endocrine physiology, reproductive physiology. | Part V • Respiratory Physiology 18 A CT I V E Ventilation and the Mechanics of Breathing LE ARNING OBJ E CTIVE S Respiratory Physiology Upon mastering the material in this chapter, you should be able to: • Explain how a pleural pressure is generated. • Describe how transairway pressure maintains airway patency. • Explain how changes in alveolar pressure move air in and out of the lungs. • Explain how spirometry measures lung volumes and airflow in patients. • Explain why alveolar ventilation measures the amount of fresh air that enters the lung. • Describe how expired carbon dioxide can be used to measure alveolar ventilation. • Explain how alveolar ventilation influences blood arterial B of oxygen and carbon dioxide between the atmosphere and the lungs. The second level involves the exchange of oxygen and carbon dioxide and occurs between the systemic blood and the metabolically active tissue. The movement of oxygen and carbon dioxide in and out of cells occurs by simple diffusion. The human lungs are so efficiently designed that gas exchange can increase >20-fold to remove carbon dioxide and to supply oxygen to tissues in order to meet the body’s energy demands. The gas exchange process rarely limits our activity. For example, a marathon runner who staggers across the 26-mile finish line in <3 hours or someone who swims the English Channel in record time is rarely limited by the amount of oxygen taken up by the lungs. These examples of human activity not only underscore the functional capacity of the lungs but also illustrate the important role respiration plays in our extraordinary adaptability to our environment. The second stage of respiration is known as cellular respiration, a series of complex metabolic reactions that break down molecules of food, releasing carbon dioxide and energy. Recall that oxygen is required in the final step of cellular respiration to serve as an electron acceptor in the process by which cells obtain energy. reathing is .

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