tailieunhanh - Chromatographic Analysis of Pharmaceuticals: Second Edition - John A. Adamovics

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. | Chromatographic Analysis of Pharmaceuticals Second Edition, Revised and Expanded edited by John A. Adamovics Cytogen Corporation Princeton, New Jersey Marcel Dekker, Inc. New York-Basel «Hong Kong Preface ISBN: 0-8247-9776-0 The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the address below. This book is printed on acid-free paper. Copyright © 1997 by Marcel Dekker, Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Marcel Dekker, Inc. 270 Madison Avenue, New York, New York 10016 Current printing (last digit): 10 9 8 7 6 5 4 3 2 1 PRINTED IN THE UNITED STATES OF AMERICA The first edition of Chromatographic Analysis of Pharmaceuticals was published in 1990. The past years have allowed me to evaluate leads that I uncovered during the researching of the first edition, such as the first published example of the application of chromatography to pharmaceutical analysis of medicinal plants. This and other examples are found in a relatively rare book, Uber Kapillaranalyse und ihre Anwendung in Pharmazeutichen Laboratorium (Leipzig, 1992), by H. Platz. Capillary analysis, the chromatographic technique used, was developed by Friedlieb Runge in the mid-1850s and was later refined by Friedrich Goppelsroeder. The principle of the analysis was that substances were absorbed on filter paper directly from the solutions in which they were dissolved; they then migrated to different points on the filter paper. Capillary analysis differed from paper chromatography in that no developing solvent was used. We find that, from these humble beginnings 150 years ago, the direct descendant of this technique, paper chromatography, is still widely used