tailieunhanh - Ebook Case-Based brain imaging (2nd edition): Part 2

(BQ) Part 2 the book "Case-Based brain imaging" presents the following contents: Neurodegenerative/white matter diseases/metabolic, trauma, congenital/developmental malformations and syndromes, cranial nerves. | Section IV Neurodegenerative White Matter Diseases Metabolic Case 85 Clinical Presentation A 28-year-old woman presents with leg weakness. Radiologic Findings A B C D E Fig. Multiple axial T2-W FLAIR images demonstrate scattered periventricular foci of T2 prolongation radiating from ventricles A within the left brachium pontis B and within the splenium of the corpus callosum C in a pattern typical of demyelination as seen F with multiple sclerosis. The lesion within the corpus callosum demonstrates enhancement on the postcontrast T1W image D and restricted diffusion on the DWI E with matching ADC F signal consistent with an active region of demyelination. Diagnosis Multiple sclerosis MS Differential Diagnosis Acute disseminated encephalomyelitis more common in children deep gray nuclear involvement common and colossal involvement uncommon indistinguishable from first episode of MS Microvascular ischemic disease older patient typically sparing of corpus callosum and subcortical U fibers lack of enhancement Vasculitis small chronic infarctions and leptomeningeal enhancement may be seen Neoplasm typically more mass effect rarely involves the corpus callosum unless glioblastoma or lymphoma .