tailieunhanh - ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FORM POULTRY WORKERS, PATIENTS AND CHICKEN IN THE EASTERN PROVINCE OF SAUDI ARABIA

The reported rates of illnesses and injuries in the poultry industry are likely to be the tip of the iceberg [National Research Council, 2003]. Workers often see the hazards as part of the job, or they move on to other jobs as they begin to develop symptoms, especially when those symptoms limit work activity [Human Rights Watch, 2004; Lipscomb et al., 2005]. Among immigrant—particularly undocumented— workers, reporting illnesses and injuries is difficult because of language barriers and brings with it the fear of job loss or deportation [Fink, 1998; Government Accountability Office, 2005]. Because the only sources of occupational health statistics for the poultry industry are Occupational Safety and Health Administration (OSHA). | Tropical Medicine and International Health VOLUME 4 NO 4 pp 278-283 APRIL 1999 Antibiotic resistance of Escherichia coli isolated from poultry workers patients and chicken in the eastern province of Saudi Arabia Mastour S. Al-Ghamdi1 Fikry El-Morsy2 Zaki H. Al-Mustafa1 Mustafa Al-Ramadhan3 and Mohammad Hanif4 1 Department of Pharmacology College of Medicine King Faisal University 2 Department of Microbiology College of Medicine King Faisal University 3 College of Veterinary Medicine King Faisal University 4 Department of Family and Community Medicine College of Medicine King Faisal University Saudi Arabia Summary The prevalence of antibiotic-resistant Escherichia coli isolates from faecal samples from 117 poultry industry workers 100 patients and119 healthy chicken were compared. Resistance of E. coli chicken isolates to ampicillin chloramphenicol gentamicin spectinomycin tetracycline and trimethoprim sulphamethoxazole TMP SMX range 57 - were significantly higher than those isolated from patients range - and workers range 35 - . However for drugs not used in poultry such as amoxicillin cluvalanate AMX CLV ceftazidime and nitrofurantoin resistance rates of chicken isolates range 0 - were significantly lower than those of patient isolates range - 30 . Resistance to spectinomycin reached 96 in E. coli chicken isolates and 71 in organisms isolated from humans. Use of this drug in Saudi Arabia is mostly limited to veterinary purposes. Multidrug resistance is alarmingly high in all groups but was highest in chicken isolates . Serotyping of E. coli isolates showed that 27 of the organisms isolated from patients were overlapping with of the chicken isolates indicating the possibility of chicken being a source of the resistance pool for humans. We therefore call for the banning of antibiotics in the poultry industry as growth promoters and recommend that their use be restricted to treating infections. keywords Escherichia coli microbial