tailieunhanh - Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia)

The 2006 Global BioMillennium Conference took place in Tbilisi, Georgia, on 13–17 July 2006. The Conference was focused on key aspects of gene expression processes. Characteristic of state-of-the-art research in the life sciences, the invited lectures spanned approaches in cell biology, gene expression, and protein function. | REVIEW ARTICLE It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology Tbilisi Georgia Hermona Soreq1 and Alik Honigman2 1 Department of BiologicalChemistry The Hebrew University of Jerusalem Israel 2 Department of Virology The Hebrew University of Jerusalem Israel Keywords alternative splicing cellular imaging chromatin ribosomes siRNA ubiquitin Correspondence H. Soreq Department of Biological Chemistry The Hebrew University of Jerusalem Jerusalem 91904 Israel Fax 972 2 652 0258 Tel 972 2 658 5109 E-mail soreq@ The 2006 Global BioMillennium Conference took place in Tbilisi Georgia on 13-17 July 2006. The Conference was focused on key aspects of gene expression processes. Characteristic of state-of-the-art research in the life sciences the invited lectures spanned approaches in cell biology gene expression and protein function. A particular aspect that is special to the BioMillenium series of conferences this has been the 10th in this series is the emphasis on new and emerging technologies the various experts in the subfields that were covered presented what in their view should be critical to enabling future progress. Received 23 August 2006 revised 20 November 2006 accepted 11 December 2006 doi Introduction Improved resolution in time and space is the hallmark of studies in diverse subfields of the life sciences including epigenetics structural biology and electron tomography. Combined with dynamic imaging of immune cells and with data management of cDNA microarrays such studies yield reliable synchronization of cell cycle events with one goal being the development of specific microRNA and protein signatures of particular tumor cell types and another being to follow the dynamics of neurite growth in the live brains of mice. Meeting report From birth to death of gene products Until recently epigenetic mechanisms have been