tailieunhanh - Báo cáo y học: " Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients | BioMed Central BMC Psychiatry Research article Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients Haya Ascher-Svanum 1 Xiaomei Peng2 Douglas Faries2 William Montgomery3 and Peter M Haddad4 5 Address 1Eli Lilly and Company Indianapolis IN USA 2Lilly USA LLC Indianapolis IN USA 3Eli Lilly Australia Pty Ltd Macquarie Park Australia 4Greater Manchester West Mental Health NHS Foundation Trust Manchester UK and 5Neuroscience and Psychiatry Unit School of Psychiatry and Behavioural Sciences University of Manchester Manchester UK Email Haya Ascher-Svanum - haya@ Xiaomei Peng - x_peng@ Douglas Faries - William Montgomery - Montgomery_bill@ Peter M Haddad - peterhaddad@ Corresponding author Open Access Published 29 July 2009 Received 1 December 2008 BMC Psychiatry 2009 9 46 doi 1471-244X-9-46 Accepted 29 July 2009 This article is available from http 1471-244X 9 46 2009 Ascher-Svanum et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediately precede the initiation of depot typical antipsychotics in the usual treatment of schizophrenia patients with a recent history of nonadherence with oral antipsychotic regimens. Methods Data were drawn from a large multisite 3-year prospective noninterventional observational study of persons treated for schizophrenia in the United States which was conducted between 7 1997 and 9 2003. The analytical sample