tailieunhanh - Báo cáo y học: " Relapse according to antipsychotic treatment in schizophrenic patients: a propensityadjusted analysis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Relapse according to antipsychotic treatment in schizophrenic patients: a propensityadjusted analysis | Millier et al. BMC Psychiatry 2011 11 24 http 1471-244X 11 24 BMC Psychiatry RESEARCH ARTICLE Open Access Relapse according to antipsychotic treatment in schizophrenic patients a propensity-adjusted analysis Ai iralia K li I liar1 Pm m2ni ial Io c rlnn2 3 4 la n-K infial Avnrin5 I 21 Irani Rn ar6C2 ni ial Ah t2lla21 R2C -2I Al ini liar6 Auieiie Miiiiei Emmdi lueiie Sdiion Jedn Michei Azoiin Lduieni Boyei Jdmuci Abdiied rdscdi Auquiei Mondher Toumi7 Abstract Objective To compdie the idte of ieidpse ds d function of dntipsychotic tiedtment monotherapy vs. poiyphdimdcy in schizophrenic pdtients ovei d 2-yedi period. Methods Using ddtd fiom d muiticentei cohort study conducted in France we peifoimed d piopensity-ddjusted dndiysis to exdmine the dssocidtion between the idte of ieidpse ovei d 2-yedi period dnd dntipsychotic tiedtment monotherapy vs. poiyphdimdcy . Results Oui sdmpie consisted in 183 pdtients 50 pdtients hdd dt iedst one period of ieidpse dnd 133 hdd no ieidpse . Thirty-eight peicent of the pdtients received poiyphdimdcy. The most seveieiy iii pdtients weie given poiyphdimdcy the dge dt onset of iiiness wds iowei in the poiyphdimdcy gioup p . Pdtients thdt received poiyphdimdcy diso presented d highei geneidi psychopdthoiogy PANSS subscoie p but no stdtisticdiiy significdnt difference wds found in the PANSS totdi scoie oi the PANSS positive oi negdtive subscdies. These pdtients weie moie iikeiy to be given prescriptions foi seddtive diugs p dnd dntidepiessdnt medicdtions p . Reidpse wds found in of pdtients given monotherapy dnd given poiyphdimdcy p . Aftei stidtificdtion dccoiding to quintiies of the propensity scoie which eiimindted dii significdnt diffeiences foi bdseline chdidcteiistics dntipsychotic polyphdimdcy wds not stdtisticdlly dssocidted with dn inciedse of ieidpse HR . Conclusion Aftei propensity scoie ddjustment dntipsychotic poiyphdimdcy is not .

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