tailieunhanh - Báo cáo y học: "Natriuretic peptide determinations in critical care medicine: part of routine clinical practice or research test only"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:Natriuretic peptide determinations in critical care medicine: part of routine clinical practice or research test only? | Available online http content 13 1 105 Commentary Natriuretic peptide determinations in critical care medicine part of routine clinical practice or research test only Paul O Collinson Department of Chemical Pathology and Department of Cardiology St George s Hospital and Medical School London SW17 0QT UK Corresponding author Paul O Collinson Published 12 January 2009 This article is online at http content 13 1 105 2009 BioMed Central Ltd Critical Care 2009 13 105 doi cc7133 See related research by Coquet et al. http content 12 6 R137 Abstract Measurement of N-terminal pro-B-type natriuretic peptide has been shown a good rule-out test for cardiac dysfunction in patients in the intensive care unit. The peptide measurement should not be used as a replacement for other forms of monitoring and performs best as a diagnostic test when interpreted together with other clinical findings and investigations. At a cutoff value similar to that found in other clinical studies in acute decompensated heart failure measurement of N-terminal pro-B-type natriuretic peptide offers an additional tool for diagnostic assessment of patients presenting to the intensive care physician. Measurement of the B-type natriuretic peptide BNP and mesurement of the N-terminal portion of the prohormone N-terminal pro-B-type natriuretic peptide NTproBNP are part of the routine assessment of patients presenting with acute dyspnoea. The measurement of BNP NTproBNP is now included in the recommendations from professional societies. Coquet and colleagues 1 have studied NTproBNP measurement in the critical care population. They compared the diagnostic performance of NTproBNP using a final diagnosis of cardiac dysfunction based on a combination of clinical and echocardiographic criteria. Using this diagnosis as the dichotomous variable the authors performed receiver operating characteristic curve analysis and showed that the area .