tailieunhanh - Báo cáo y học: "Acute kidney injury on admission to the intensive care unit: where to go from here"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Acute kidney injury on admission to the intensive care unit: where to go from here? | Available online http content 1 2 6 189 Commentary Acute kidney injury on admission to the intensive care unit where to go from here Marlies Ostermann Open Access Guy s and St Thomas Hospital Department of Critical Care Westminster Bridge Road London SE1 7EH UK Corresponding author Marlies Ostermann Published 7 Nov 2008 Critical Care 2008 12 189 doi cc7096 This article is online at http content 12 6 189 2008 BioMed Central Ltd See related research by Kolhe et al. http content 1 2 S1 S2 Abstract Acute kidney injury AKI is a common problem especially in critically ill patients. In Critical Care Kolhe and colleagues report that of 276 731 patients in 170 intensive care units ICUs in the UK had evidence of severe AKI within the first 24 hours of admission to ICU. ICU and hospital mortality as well as length of stay in hospital were significantly increased. In light of this serious burden on individuals and the health system in general the following commentary discusses the current state of knowledge of AKI in ICU and calls for more attention to preventive strategies. Acute kidney injury AKI has been the focus of numerous publications and research projects in the past 5 years 1-4 including the study by Kolhe and colleagues 1 in Critical Care. Interestingly as facts about AKI and its impact on prognosis emerged areas of uncertainty and controversy became apparent 5 6 . It is now well known that AKI affects a large number of patients although the exact incidence is variable that AKI per se is associated with an increased risk of death and that patients who need renal replacement therapy RRT have a higher risk of dying 2-4 7 8 . There is also evidence that AKI is a dynamic process with many patients progressing through different stages of severity and that early AKI appears to have a better prognosis than late AKI 7 . Numerous studies have identified factors that influence the prognosis of .

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