tailieunhanh - Báo cáo y học: " Year in review 2007: Critical Care – multiple organ failure and sepsi"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Year in review 2007: Critical Care – multiple organ failure and sepsis. | Available online http content 12 5 228 Review Year in review 2007 Critical Care - multiple organ failure and sepsis James M O Brien Jr1 Naeem A Ali1 and Edward Abraham2 1 Division of Pulmonary Allergy Critical Care and Sleep Medicine Center for Critical Care The Ohio State University Medical Center 201 Davis HLRI 473 West 12th Avenue Columbus OH 43210 USA 2Department of Medicine University of Alabama at Birmingham School of Medicine 420 Boshell Building 1808 7th Avenue South Birmingham Alabama 35294 USA Corresponding author James M O Brien Jr Published 14 October 2008 This article is online at http content 12 5 228 2008 BioMed Central Ltd Critical Care 2008 12 228 doi cc6950 Abstract Several research papers published in Critical Care throughout 2007 examined the pathogenesis diagnosis treatment and prognosis of sepsis and multiorgan failure. The present review summarizes the findings and implications of the papers published on sepsis and multiorgan failure and places the research in the context of other work in the field. Introduction Nine papers exploring sepsis and multiorgan failure were published in Critical Care throughout 2007. Four of these articles examined possible pathophysiologic mechanisms underlying sepsis and organ failure. One paper explored the use of biomarkers in community-acquired infections. Three articles reported results of different therapeutic approaches to sepsis and one article evaluated the longer-term outcomes for sepsis survivors. Pathogenesis Organ-specific effects of local infection versus remote infection In an interesting study from Finland Vakkala and colleagues systematically explored the epithelial response in the gallbladders of two groups of patients with cholecystitis 1 . The authors compared gallbadders removed during open cholecystectomy from critically ill patients with acute acalculous cholecystitis n 30 from noncritically ill patients with acute calculous .

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