tailieunhanh - Báo cáo y học: "Circuit lifespan during continuous renal replacement therapy: children and adults are not equal"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Circuit lifespan during continuous renal replacement therapy: children and adults are not equal. | Available online http content 12 5 178 Commentary Circuit lifespan during continuous renal replacement therapy children and adults are not equal Zaccaria Ricci1 Isabella Guzzo2 Stefano Picca2 and Sergio Picardo1 1 Department of Pediatric Cardiology Bambino Gesù Hospital Piazza S. Onofrio 4 00100 Rome Italy 2Department of Nephrology and Urology Dialysis Unit Bambino Gesù Hospital Piazza S. Onofrio 4 00100 Rome Italy Corresponding author Zaccaria Ricci Published 16 September 2008 This article is online at http content 12 5 178 2008 BioMed Central Ltd Critical Care 2008 12 178 doi cc7000 See related research by del Castillo et al. http content 12 4 R93 Abstract In the field of continuous renal replacement therapy CRRT session length downtime and dose require detailed research which will provide information important in relation to prescription anticoagulation and circuit material choice membrane type and size vascular access site and size . In particular it appears that many of the data currently existing in the literature and accepted regarding CRRT prescription and delivery in critically ill adult patients are not strictly applicable to the paediatric setting. Furthermore many of the available paediatric studies are small retrospective or underpowered. In paediatric CRRT epidemiological investigations and prospective trials to investigate practical aspects of extracorporeal therapies are welcome and urgently needed. Del Castillo and coworkers 1 recently reported an interesting prospective study in which they collected information related to circuit life in 122 critically ill children treated with continuous renal replacement therapy CRRT . The variables significantly associated with prolonged filter life were catheters larger than Fr filters with surface area larger than m2 heparin dose greater than 15 UI kg per hour and use of haemodiafiltration. In the multivariate logistic regression