tailieunhanh - Báo cáo y học: "Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentatio"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentation. | Available online http content 12 4 219 Review Bench-to-bedside review Rare and common viral infections in the intensive care unit - linking pathophysiology to clinical presentation Nicholas Stollenwerk Richart W Harper and Christian E Sandrock Division of Pulmonary and Critical Care Medicine University of California-Davis School of Medicine Davis CA USA Corresponding author Christian Sandrock cesandrock@ Published 17 July 2008 Critical Care 2008 12 219 doi cc6917 This article is online at http content 12 4 219 2008 BioMed Central Ltd Abstract Viral infections are common causes of respiratory tract disease in the outpatient setting but much less common in the intensive care unit. However a finite number of viral agents cause respiratory tract disease in the intensive care unit. Some viruses such as influenza respiratory syncytial virus RSV cytomegalovirus CMV and varicella-zoster virus VZV are relatively common. Others such as adenovirus severe acute respiratory syndrome SARS -coronavirus Hantavirus and the viral hemorrhagic fevers VHFs are rare but have an immense public health impact. Recognizing these viral etiologies becomes paramount in treatment infection control and public health measures. Therefore a basic understanding of the pathogenesis of viral entry replication and host response is important for clinical diagnosis and initiating therapeutic options. This review discusses the basic pathophysiology leading to clinical presentations in a few common and rare but important viruses found in the intensive care unit influenza RSV SARS VZV adenovirus CMV VHF and Hantavirus. Introduction Viral infections are common causes for upper and lower respiratory tract infections and a frequent reason for outpatient office visits. Comparatively viral respiratory infections are less common in the intensive care unit ICU setting but still play an important clinical role. Most viral respiratory infections in the ICU are .

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