tailieunhanh - Salters-Nuffield Advanced Biology for Edexcel AS Biology

Salters-Nuffi eld Advanced Biology (SNAB) is much more than just another A-level specifi cation. It is a complete course with its own distinctive philosophy. h e course is supported by a comprehensive set of teaching, learning and support materials which embrace a student centred approach. SNAB combines the key concepts underpinning biology today, combined with the opportunity to gain the wider skills that biologists now need. | edexcel advancing Learning changing Lives Salters-Nuffield Advanced Biology for Edexcel AS Biology STUDENTS BOOK A PEARSON COMPANY Pearson Education Limited Edinburgh Gate Harlow Essex CM20 2JE United Kingdom 1 and Associated Companies throughout the world University of York Science Education Group 2008 First published 2005 Published as trial edition 2002 This edition published 2008 ISBN 978-1-4058-9607-8 Copyright notice All rights reserved. No part of this publication may be reproduced stored in a retrieval system 2 or transmitted in any form or by any means electronic mechanic photocopying recording or otherwise without either the prior written permission of the Publishers or a licence permitting restricted copying in the United Kingdom issued by the Copyright Licensing Agency Ltd Saffron House 6 10 Kirby Street London EC1N 8TS. Applications for the copyright owner s written permission should be addressed to the publisher. The publisher s policy is to use paper manufactured from sustainable forests. SNAB project editor Anne Scott Edited by Kate Redmond Designed and illustrated by Pantek Arts Maidstone Kent Picture research by Charlotte Lipmann Index by Laurence Errington 3 Printed and bound by Graficas Estella Bilboa Spain Contents Contributors iv 1 About the SNAB course v How to use this book vi Topic 1 Lifestyle health and risk What is cardiovascular disease 6 2 Who is at risk of cardiovascular disease 17 Risk factors for cardiovascular disease 21 Reducing the risks of cardiovascular disease 49 Topic 2 Genes and health The effects of CF on the lungs 56 3 Why is CF mucus so sticky 62 How does cystic fibrosis affect other body systems 76 How is the CFTR protein made 81 What goes wrong with DNA 86 How is cystic fibrosis inherited 90 How is cystic fibrosis treated 93 Testing for CF 96 Topic 3 Voice of the genome In the beginning 102 4 From one to many the cell cycle 114 How development is controlled 125 .