tailieunhanh - CHROMATOGRAPHY AND ITS APPLICATIONS

The third part of the book is dedicated to analysis of role of DNA methylation in cancer. According to the American Cancer Association, nearly 13% of all deaths worldwide are cancer related. Aberrant DNA methylation patterns is likely to play a causative role in cancer initiation and development. The first chapter is dedicated to investigation of DNA methylation role in the development of hepatocellular carcinoma associated with tyrosinemia. The second chapter discusses a biological relationship between DNA methylation and histone deacetylation and their role in modulating gene repression programming. This epigenetic cross-talk may be involved in gene transcription and aberrant gene silencing in tumors. The third chapter introduces the. | CHROMATOGRAPHY AND ITS APPLICATIONS Edited by Sasikumar Dhanarasu Chromatography and Its Applications Edited by Sasikumar Dhanarasu Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Vedran Greblo Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published March 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Chromatography and Its Applications Edited by Sasikumar Dhanarasu p. cm. ISBN 978-953-51-0357-8 INTECH open science I open minds free online editions of InTech Books and .