tailieunhanh - Báo cáo y học: "Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China | Yang et al. BMC Psychiatry 2011 11 84 http 1471-244X 11 84 BMC Psychiatry RESEARCH ARTICLE Open Access Validity of the 32-item Hypomania Checklist HCL-32 in a clinical sample with mood disorders in China 3t 2t 1 1 2 Hai-chen Yang 1 Cheng-mei Yuan Tie-bang Liu Ling-jiang Li Hong-jun Peng Chun-ping Liao Han Rong2 Yi-ru Fang3 and Jules Angst4 Abstract Background The 32-item Hypomania Checklist HCL-32 a questionnaire for screening bipolar disorders has been utilised in several countries but it unclear if the Chinese version of the HCL-32 is valid. Methods Consecutive patients with bipolar disorders BP N 300 and unipolar major depression UP N 156 completed the Chinese version of the HCL-32. The subjects underwent a structured clinical interview for DSM-IV Axis-I disorders SCID . Results The eigenvalues for the first three factors in the HCL-32 were calculated as active elated risktaking and irritable using factor analysis. Cronbach s alpha for the HCL-32 was calculated to be . Positive responses to twenty-eight items were significantly more frequent by patients with BP than those with UP and the other four items 7th 21st 25th and 32nd showed no such trend. Fourteen was the optimal cut-off for discriminating between BP and UP. The HCL-32 distinguished between BP-II and UP with 13 being the optimal cut-off. A cut-off of 13 yielded a sensitivity of and a specificity of between BP and UP. Conclusions This study demonstrated that the simplified Chinese version of HCL-32 was valid for patients with mood disorders. The optimal cut-off of 13 for distinguishing between BP-II and UP was valid and could be used to improve the sensitivity of screening BP-II patients when the HCL-32 is used in psychiatric settings in China. Background It is important to differentiate bipolar disorders BP from other mood disorders delayed diagnosis or misdiagnosis can prolong the suffering of patients 1-3 but accurate early diagnosis can be .

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