tailieunhanh - Báo cáo y học: " A multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations | Birchwood et al. BMC Psychiatry 2011 11 155 http 1471-244X 11 155 BMC Psychiatry STUDY PROTOCOL Open Access A multi-centre randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations 1 2 3 3 3 Max Birchwood Emmanuelle Peters Nicholas Tarrier Graham Dunn Shon Lewis Til Wykes Linda Davies Helen Lester4 and Maria Michail1 Abstract Background Command hallucinations are among the most distressing high risk and treatment resistant symptoms for people with psychosis however currently there are no evidence-based treatment options available for this group. A cognitive therapy grounded in the principles of the Social Rank Theory is being evaluated in terms of its effectiveness in reducing harmful compliance with command hallucinations. Methods Design This is a single blind intention-to-treat multi-centre randomized controlled trial comparing Cognitive Therapy for Command Hallucinations Treatment as Usual with Treatment as Usual alone. Eligible participants have to fulfil the following inclusion criteria i 16 years ii ICD-10 diagnosis of schizophrenia or related disorder iii command hallucinations for at least 6 months leading to risk of harm to self or others. Following the completion of baseline assessments eligible participants will be randomly allocated to either the Cognitive Therapy for Command Hallucinations Treatment as Usual group or the Treatment as Usual group. Outcome will be assessed at 9 and 18 months post randomization with assessors blind to treatment allocation. The primary outcome is compliance behaviour and secondary outcomes include beliefs about voices power distress psychotic symptoms together with a health economic evaluation. Qualitative interviews with services users will explore the acceptability of Cognitive Therapy for Command Hallucinations. Discussion Cognitive behaviour therapy is recommended for people with psychosis however its focus and evaluation has primarily .

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