tailieunhanh - Báo cáo y học: "Influence of sequence identity and unique breakpoints on the frequency of intersubtype HIV-1 recombination"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: "Influence of sequence identity and unique breakpoints on the frequency of intersubtype HIV-1 recombination. | BioMed Central Retrovirology Open Access Influence of sequence identity and unique breakpoints on the frequency of intersubtype HIV-I recombination Heather A Baird1 2 Yong Gao1 Román Galetto3 Matthew Lalonde1 4 Reshma M Anthony5 Véronique Giacomoni3 Measho Abreha1 Jeffrey J Destefano5 Matteo Negroni3 and Eric J Arts 1 2 Address 1Division of Infectious Diseases Department of Medicine Case Western Reserve University Cleveland Ohio 44106 USA 2Department of Pharmacology Case Western Reserve University Cleveland Ohio 44106 USA 3Unité des Regulation Enzymatique et Activités Cellulaires Institut Pasteur Paris Cedex 15 75724 France 4Department of Biochemistry Case Western Reserve University Cleveland Ohio 44106 USA and 5Department of Cell Biology and Molecular Genetics University of Maryland College Park MD 20742 USA Email Heather A Baird - heather_baird@ Yong Gao - yxg18@ Román Galetto - rgaletto@ Matthew Lalonde - msl18@ Reshma M Anthony - ranthony@ Véronique Giacomoni - vgiacomoni@ Measho Abreha - Jeffrey J Destefano - jdestefa@ Matteo Negroni - matteo@ Eric J Arts - eja3@ Corresponding author Published 12 December 2006 Received II October 2006 Accepted 12 December 2006 Retrovirology 2006 3 91 doi 1 742-4690-3-9 1 This article is available from http content 3 1 91 2006 Baird et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background HIV-1 recombination between different subtypes has a major impact on the global epidemic. The generation of these intersubtype recombinants follows a defined set of events starting with dual infection of a host cell heterodiploid virus production strand .