tailieunhanh - Báo cáo y học: " HTLV-1 Tax: centrosome amplification and cancer Anne Pumfery1, Cynthia de la Fuente2 and Fatah "

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: " HTLV-1 Tax: centrosome amplification and cancer Anne Pumfery1, Cynthia de la Fuente2 and Fatah. | Retrovirology BioMed Central Open Access HTLV-1 Tax centrosome amplification and cancer Anne Pumfery1 Cynthia de la Fuente2 and Fatah Kashanchi 3 4 Address 1Seton Hall University Department of Biology South Orange NJ 07079 USA 2The Rockefeller University Laboratory of Virology and Infectious Disease New York NY 10021 USA 3The George Washington University Medical Center Department of Biochemistry and Molecular Biology Washington DC 20037 USA and 4The Institute for Genomic Research Rockville Maryland 20850 USA Email Anne Pumfery - bcmamp@ Cynthia de la Fuente - cdelafuent@ Fatah Kashanchi - bcmfxk@ Corresponding author Published 09 August 2006 Received 18 July 2006 Retrovirology 2006 3 50 doi 1742-4690-3-50 Accepted 09 August 2006 This article is available from http content 3 1 50 2006 Pumfery et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract During interphase each cell contains a single centrosome that acts as a microtubule organizing center for cellular functions in interphase and in mitosis. Centrosome amplification during the S phase of the cell cycle is a tightly regulated process to ensure that each daughter cell receives the proper complement of the genome. The controls that ensure that centrosomes are duplicated exactly once in the cell cycle are not well understood. In solid tumors and hematological malignancies centrosome abnormalities resulting in aneuploidy is observed in the majority of cancers. These phenotypes are also observed in cancers induced by viruses including adult T cell lymphoma which is caused by the human T cell lymphotrophic virus Type 1 HTLV-1 . Several reports have indicated that the HTLV-1 transactivator Tax is .

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.