tailieunhanh - Báo cáo y học: " Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài:" Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV. | Retrovirology BioMed Central Research Open Access Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus JSRV closely resembles lung cancer in sheep infected with JSRV Sarah K Wootton1 Michael J Metzger1 Kelly L Hudkins2 Charles E Alpers2 Denis York3 James C DeMartini4 and A Dusty Miller 1 2 Address 1Division of Human Biology Fred Hutchinson Cancer Research Center Seattle Washington 98109 USA 2Department of Pathology University of Washington Seattle Washington 98195 USA 3Molecular Diagnostic Services Westville 3630 South Africa and 4Department of Microbiology Immunology and Pathology Colorado State University Fort Collins Colorado 80523 USA Email Sarah K Wootton - swootton@ Michael J Metzger - metzgerm@ Kelly L Hudkins - kellylee@ Charles E Alpers - calp@ Denis York - mds@ James C DeMartini - A Dusty Miller - dmiller@ Corresponding author Published 19 December 2006 Received 20 October 2006 Accepted 19 December 2006 Retrovirology 2006 3 94 doi 186 1742-4690-3-94 This article is available from http content 3 1 94 2006 Wootton et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Jaagsiekte sheep retrovirus JSRV causes a lethal lung cancer in sheep and goats. Expression of the JSRV envelope Env protein in mouse lung by using a replication-defective adeno-associated virus type 6 AAV6 vector induces tumors resembling those seen in sheep. However the mouse and sheep tumors have not been carefully compared to determine if Env expression alone in mice can account for the disease features observed in sheep or whether additional aspects of virus .

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.